Spastic paraplegia four (SPG4; also known as SPAST-HSP) is characterised by insidiously progressive bilateral decrease-limb gait spasticity. Over 50% of influenced individuals have some weak point in the legs and impaired vibration sense for the ankles.?? ????? ???? ??? ???? ?? ??? ? ?? ???? ??? ? ????. ?? ????? ??? ????? ??? ???? ?? ???? ??????!A